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Bio-Fires – An Eco-Friendly Alternative to Real Fires Biofires are a warm and cozy way to heat your home without the harmful gas or soot. They are easy to set up as an electric fire. The BARDA contract will support the development of the BioFire emerging CoV panel, a nucleic-acid Amplification test that will be used in conjunction with BioFire filmArray Systems for detection of known and emerging human acoronaviruses from nasopharyngeal oropharyngeal swabs as well as saliva samples. Eco-friendly Bioethanol is an eco-friendly alternative to wood or gas. The fuel is made from plant by-products, and employs an organic process to convert sugars into alcohol. It is a better option over other fireplaces as it does not emit harmful emissions, and has a lower carbon footprint. Bioethanol is also a more secure alternative to other types of fires because it doesn't produce soot or smoke. It does not require a flue and can be used anywhere in the home or garden. A multi-drug resistant (MDR) bacteria is one of the most dangerous health threats today. New testing methods can identify MDR bacteria early and prevent any further complications. One test that can help is the BioFire FilmArray multiplex PCR system. This test uses an approach based on symptoms to identify the most frequent pathogens that cause sepsis. The results are accessible within an hour, meaning providers can begin treatment right away. Molecular PCR is a process that amplifies DNA or RNA molecules into millions or billions of copies. This allows you to test small amounts of body fluids or tissues for the presence of certain genetic sequences. It is an invaluable instrument for lab professionals, and it can help them diagnose serious illnesses in a timely and cost-effective manner. The BioFire FilmArray PCR system is an innovative instrument for diagnosing infectious diseases and can be used for a wide variety of applications in hospitals and labs. In the case of respiratory tests the simplest swab could be wiped across your nose and sent to the lab for analysis. BioFire's system provides a fast turnaround time, allowing clinicians to respond quickly. This means that patients will enjoy better outcomes and will not have to wait for the results. The Chanouf Farm-Biofire company developed an Agroforestry waste recycling unit which utilizes pear and olive tree waste to create biochar and biomass energy. The resulting products are offered to the public as an eco-friendly alternative to traditional wood charcoal and coal briquettes. In addition the bio-waste products can be burned in a Kachelofen fireplace which produces radiant heat that is a green alternative to electric and gas fires. Clean burning When you use a bio-fire, you not only save energy but also help the environment. Bioethanol's combustion does not produce harmful gases such as carbon dioxide. Instead, it releases only water vapour and heat. This makes it a safer and healthier option for indoor use. Ethanol is produced by the fermentation of sugars in plants and is classified as an energy source that is renewable. This means it can be produced quickly and won't run out as fossil fuels such as oil and coal. Bioethanol helps reduce dependence on imports from abroad and reduces the risks that come with supply shortages. Bio-fires are very easy to install and can be used in existing fireplace openings, or as a freestanding unit. They are a good alternative to wood and gas fires. They are also ideal for offices and homes that do not have a chimney or flue. When a bio-fire is ignited the burner is equipped with a special media that absorbs the liquid ethanol fuel and makes it available for combustion. The ethanol fuel is ignited in the flames, and the vapors are released into the air via the vent. This gives the flames a more natural look and a mesmerising beauty which isn't matched by wood or gas fires. Another benefit of bio-fires is that they don't need a flue or vent to replenish the oxygen that is consumed during combustion. They also don't create carbon monoxide, which is required to be vented into the room in gas fires with open fronts. The BioFire Respiratory panel makes use of multiplex PCR to simultaneously test for respiratory pathogens. This takes about an hour. This enables doctors to identify and eliminate respiratory diseases quicker than they could with conventional lab tests that require patient visits. This reduces time and costs for both patients and the health healthcare system. Safe indoors Bio-fires can be used indoors much more safely than real fires since they don't release smoke or ash, as well as carcinogenic fumes. They also do not emit carbon monoxide, which could be deadly if inhaled. The bio-ethanol fuel they use is flammable however it is important to be extremely careful when handling the burner and refilling your fire. It should be replenished only after the burner has been shut off and the fire is cool. Any spills should be cleaned immediately. The company's diagnostic FilmArray system, BioFire Torch and BioFire 2.0—are simple to use and can run eight different diagnostic panels approved by the US Food and Drug Administration as well as three additional panels approved for emergency use and six environmental test panel. The tests include a respiratory panel developed to quickly recognize and distinguish respiratory illnesses including COVID-19, emerging coronaviruses, and COVID-19. Its COVID-19 panel has been awarded a grant by the Biomedical Advanced Research and Development Initiative (BARDI), which is part of the US Department of Defense's Strategic Access Program. The COVID-19 test is an antigen-based system, allowing clinicians to distinguish between the symptoms caused by COVID-19 and other respiratory infections with the same precision as the rapid antigen tests currently in use. Additionally, the company is developing an SARS-CoV-2 assay for their Respiratory 2.1 Panel. This multiplexed nucleic acids amplifying test will be available for use on the BioFire FilmArray 2.0 and Torch Systems, and will detect SARS-CoV-2 as well as 21 other respiratory pathogens within nasopharyngeal or saliva samples in less than an hour. The test will be developed in a short time frame, and FDA approval for EUA and the 510(k) will be expected to be granted by Q3 2020. Bio-ethanol flame effect fires are safe to use but should be kept clear of combustible items such as curtains, pillows, and blankets. They should not be placed near anything that may catch fire and you should keep flammable objects at least 10 feet away from them. The bioethanol fuel must be stored in a location that is dry and secure where pets or children are unable to reach it. Simple to use A bioethanol fireplace is easy to operate and doesn't have a flue to worry about. All you need is a location to place it in and some fuel. After you've filled the burner, light it. This will create an appearance of an actual flame. After bio fuel fires has been ignited it will heat the room with very little or no smoke. It will also produce a lot of heat, just like wood-burning fires would. They are also easy to maintain and do not require any maintenance. A quick clean is all they require. Contrary to most tests that are rapid however, the BioFire RP2.1-EZ test uses a syndromic approach to identify the most common signs of infection and can return results within 45 minutes. This test is designed for patients with upper respiratory symptoms and has a 98% specificity rate. The test can identify 19 viruses and three bacteria in one sample which makes it a great choice for patient management. The BioFire system integrates multiplex PCR testing, sample preparation, and report on results into an integrated platform. This allows laboratories to simplify their workflow and eliminate the need for a serial procedure that involves individual and send-out tests. This can result in improved outcomes for patients by allowing the appropriate test to be administered the first time, and by removing the need for expensive tests that are based on a culture. Additionally, the BioFire system can detect pathogens and their resistance genes to antimicrobials at a molecular level, providing data that is more precise than traditional methods. Molecular diagnostics are being used to improve the care of patients and outcomes. The BioFire panel RP2.1+ employs an syndromic technique to simultaneously target 23 pathogens that are frequently implicated in respiratory infections. The test can be run on the BioFire FilmArray 2.0 and Torch systems and delivers results in about 45 minutes. In the US this test is currently available under FDA Emergency Use Authorization (EUA), and will be commercially available after initial DoD demand is satisfied. Additionally, the BioFire Defense Team has created an automated, sample-to-result assay that allows for the quick identification of COVID-19. This assay is in the process of development and will be available once initial DoD demand is fulfilled.